Journal: Journal of Orthopaedic Translation
Article Title: Relieving oxidative stress microenvironment and promoting vascularized bone formation to treat femoral head necrosis using 3D-printed scaffold with ultralong-term multienzyme-like activity
doi: 10.1016/j.jot.2025.06.010
Figure Lengend Snippet: Histological analysis of the femoral head after treatment. (a) Representative H&E staining images of the femoral head after treatment. Many empty lacunae (indicated by black arrows) were observed in the control (only core decompression without scaffold implantation) and PLGA groups at 6 and 12 weeks postsurgery. More vessel formation (indicated by yellow and red arrows) was observed in the PLGA/Mn2.5 group relative to other groups. The proportion of empty lacunae (b), the trabecular bone area (c), and the number of vessels (d) within femoral head derived from the H&E staining images ( n = 3). (e) Immunohistochemical staining of CD31 and VEGF expression within femoral head at 12 weeks postsurgery. S represents the area of the scaffold.
Article Snippet: Expression of CD31 (antibody: HUABIO, HA601240 , China) and VEGF (antibody: Bioss, bs-1313R, China) in cartilage sections was studied by immunohistological staining.
Techniques: Staining, Control, Derivative Assay, Immunohistochemical staining, Expressing